C0009504 - A 77-kDa subcomponent of complement C1, encoded by gene C1S, is a SERINE PROTEASE existing as a proenzyme (homodimer) in the intact complement C1 complex. Upon the binding of COMPLEMENT C1Q to antibodies, the activated COMPLEMENT C1R cleaves C1s into two chains, A (heavy) and B (light, the serine protease), linked by disulfide bonds yielding the active C1s. The activated C1s, in turn, cleaves COMPLEMENT C2 and COMPLEMENT C4 to form C4b2a (CLASSICAL C3 CONVERTASE). 1/10
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293,031 терминов и синонимов из MeSH и LOINC

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Terms, descriptions
CUI    C0009504
RussianMedical Subject Headings Russian D003173 L3353100preferred S3880560 Y КОМПЛЕМЕНТА КОМПОНЕНТ 1S
RussianMedical Subject Headings Russian D003173 L0897265no S1101082 Y KOMPLEMENT, KOMPONENT 1S
RussianMedical Subject Headings Russian D003173 L1512583no S1808492 Y C1 ESTERAZA
RussianMedical Subject Headings Russian D003173 L1518475no S1814384 Y ESTERAZA KOMPONENTA 1 KOMPLEMENTA
RussianMedical Subject Headings Russian D003173 L2227562no S2565784 Y KOMPLEMENT 1S
RussianMedical Subject Headings Russian D003173 L2227580no S2565802 Y KOMPLEMENTA 1 ESTERAZA
RussianMedical Subject Headings Russian D003173 L2227588no S2565810 Y KOMPLEMENTA KOMPONENT 1S
RussianMedical Subject Headings Russian D003173 L3335242no S3862681 Y C1 ЭСТЕРАЗА
RussianMedical Subject Headings Russian D003173 L3353039no S3880522 Y КОМПЛЕМЕНТ 1S
RussianMedical Subject Headings Russian D003173 L3353060no S3880600 Y КОМПЛЕМЕНТ, КОМПОНЕНТ 1S
RussianMedical Subject Headings Russian D003173 L3353082no S3880542 Y КОМПЛЕМЕНТА 1 ЭСТЕРАЗА
RussianMedical Subject Headings Russian D003173 L3378331no S3905824 Y ЭСТЕРАЗА КОМПОНЕНТА 1 КОМПЛЕМЕНТА
RussianMedical Subject Headings Russian D003173 L5697450no S6530486 Y КОМПЛЕМЕНТ C1S
RussianMedical Subject Headings Russian D003173 L6972488no S8107479 Y KOMPLEMENT C1S
Medical Subject Headings A8408332 AT53894353 A 77-kDa subcomponent of complement C1, encoded by gene C1S, is a SERINE PROTEASE existing as a proenzyme (homodimer) in the intact complement C1 complex. Upon the binding of COMPLEMENT C1Q to antibodies, the activated COMPLEMENT C1R cleaves C1s into two chains, A (heavy) and B (light, the serine protease), linked by disulfide bonds yielding the active C1s. The activated C1s, in turn, cleaves COMPLEMENT C2 and COMPLEMENT C4 to form C4b2a (CLASSICAL C3 CONVERTASE).