C0019629 - Found on virtually every cell, MHC (Major Histocompatibility, HLA) Class-I (Antigens) Proteins consist of noncovalently bound polymorphic 44-kDa MHC membrane glycoprotein and nonpolymorphic 12-kDa b2-microglobulin. The HLA antigens are encoded by closely linked multiallelic genes of the HLA (MHC) complex, a region containing several genetic loci (HLA-A, -B, -C, -DP, -DQ, -DR, -MB, -MT, and -Te). 1/10
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Terms, descriptions
CUI    C0019629
RussianMedical Subject Headings Russian D015395 L3345555preferred S3873035 Y ГИСТОСОВМЕСТИМОСТИ АНТИГЕНЫ КЛАССА I
RussianMedical Subject Headings Russian D015395 L0894829no S1098646 Y GISTOSOVMESTIMOSTI ANTIGENY KLASSA I
RussianMedical Subject Headings Russian D015395 L1508885no S1804794 Y ANTIGENY GISTOSOVMESTIMOSTI KLASSA I
RussianMedical Subject Headings Russian D015395 L1526479no S1822388 Y KLASSA I ANTIGENY
RussianMedical Subject Headings Russian D015395 L3338864no S3866348 Y АНТИГЕНЫ ГИСТОСОВМЕСТИМОСТИ КЛАССА I
RussianMedical Subject Headings Russian D015395 L3352289no S3879775 Y КЛАССА I АНТИГЕНЫ
Medical Subject Headings A0068358 AT141595967 Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits of class I antigens and play an important role in determining the serological specificity of the surface antigen. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells.
(CPTSP) CRISP Thesaurus A1174913 AT51224774 large transmembrane, polymorphic glycoproteins noncovalently associated with nonpolymorphic beta 2-microglobulin; in humans, three structural genes on chromosome 6 code for the HLA-A, HLA-B and HLA-C antigens, and in mice three genes on chromosome 17 code for the H-2 antigens; class I antigens are found on most nucleated cells, are recognized during graft rejection, restrict cell-mediated lysis of virus infected cells, and are associated with rheumatologic diseases and certain malignant disorders.
NCI Thesaurus A7604572 AT197978819 Found on virtually every cell, MHC (Major Histocompatibility, HLA) Class-I (Antigens) Proteins consist of noncovalently bound polymorphic 44-kDa MHC membrane glycoprotein and nonpolymorphic 12-kDa b2-microglobulin. The HLA antigens are encoded by closely linked multiallelic genes of the HLA (MHC) complex, a region containing several genetic loci (HLA-A, -B, -C, -DP, -DQ, -DR, -MB, -MT, and -Te).