C0028027 - The active form of vitamin B3 and a component of the coenzyme nicotinamide adenine dinucleotide (NAD). Niacinamide acts as a chemo- and radio-sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia. This agent also inhibits poly(ADP-ribose) polymerases, enzymes involved in the rejoining of DNA strand breaks induced by radiation or chemotherapy.

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Lang Dictionary CODE			LUI	preferred no	SUI	preference Yes / No	Terms, descriptions
							CUI C0028027

Russian	Medical Subject Headings Russian	D009536	L3360190	preferred	S3887677	Y	НИКОТИНАМИД
Russian	Medical Subject Headings Russian	D009536	L0900336	no	S1104153	Y	NIKOTINAMID
Russian	Medical Subject Headings Russian	D009536	L1533213	no	S1829122	Y	NIATSINAMID
Russian	Medical Subject Headings Russian	D009536	L1548582	no	S1844491	Y	VITAMIN B3
Russian	Medical Subject Headings Russian	D009536	L1548597	no	S1844506	Y	VITAMIN RR
Russian	Medical Subject Headings Russian	D009536	L3342865	no	S3870346	Y	ВИТАМИН B3
Russian	Medical Subject Headings Russian	D009536	L3342891	no	S3870392	Y	ВИТАМИН РР
Russian	Medical Subject Headings Russian	D009536	L3360154	no	S3887641	Y	НИАЦИНАМИД
	Medical Subject Headings				A0092135	AT38137570	An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
	(CPTSP) CRISP Thesaurus				A0484741	AT51222992	B complex vitamin used in the prophylaxis and treatment of pellagra; functions as a component of the coenzyme NAD (Nicotinamide-Adenine Dinucleotide).
	Medical Subject Headings Czech				A13050043	AT231357959	Faktor PP, amid nikotinové kyseliny, protipelagrický vitamin obsažený jako součást dehydrogenáz v kvasnicích, mléce a obilných klíčcích. (cit. Velký lékařský slovník online, 2017 http://lekarske.slovniky.cz)
	PDQ				A4346047	AT70660939	The active form of vitamin B3 and a component of the coenzyme nicotinamide adenine dinucleotide (NAD). Niacinamide acts as a chemo- and radio-sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia. This agent also inhibits poly(ADP-ribose) polymerases, enzymes involved in the rejoining of DNA strand breaks induced by radiation or chemotherapy. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42044&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42044&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2327" NCI Thesaurus)
	NCI NCI Dictionary of Cancer Terms				A7572489	AT197954281	A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Niacinamide helps some enzymes make energy in the cell. It is found in many plant and animal products. It is water-soluble (can dissolve in water) and must be taken in daily. It is being studied to increase the effect of radiation therapy on tumor cells.
	NCI Thesaurus				A7572489	AT198090093	The active form of vitamin B3 and a component of the coenzyme nicotinamide adenine dinucleotide (NAD). Niacinamide acts as a chemo- and radio-sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia. This agent also inhibits poly(ADP-ribose) polymerases, enzymes involved in the rejoining of DNA strand breaks induced by radiation or chemotherapy.