UMLS Hierarchy Tracer (Ancestors & Descendants)

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Target Concept: Guanine Nucleotide Exchange Factors (C0120465)

Ancestor Paths (Parents/Root)

Ancestor Path 1 (Root Source: MSH)

  1. CUI: - / Source: MSH
  2. CUI: - / Source: MSH
  3. MeSH Descriptors CUI: C1256739 / Source: MSH
  4. Topical Descriptor CUI: C1256741 / Source: MSH
  5. Chemicals and Drugs (MeSH Category) CUI: C0007995 / Source: MSH
  6. Amino Acids, Peptides, and Proteins CUI: C0002526 / Source: MSH
  7. Peptides CUI: C0030956 / Source: MSH
  8. Intracellular Signaling Peptides and Proteins CUI: C1449791 / Source: MSH
  9. GTP-Binding Protein Regulators CUI: C0751981 / Source: MSH
  10. Guanine Nucleotide Exchange Factors (START) CUI: C0120465 / Source: MSH

Ancestor Path 2 (Root Source: MSH)

  1. CUI: - / Source: MSH
  2. CUI: - / Source: MSH
  3. MeSH Descriptors CUI: C1256739 / Source: MSH
  4. Topical Descriptor CUI: C1256741 / Source: MSH
  5. Chemicals and Drugs (MeSH Category) CUI: C0007995 / Source: MSH
  6. Amino Acids, Peptides, and Proteins CUI: C0002526 / Source: MSH
  7. Proteins CUI: C0033684 / Source: MSH
  8. Intracellular Signaling Peptides and Proteins CUI: C1449791 / Source: MSH
  9. GTP-Binding Protein Regulators CUI: C0751981 / Source: MSH
  10. Guanine Nucleotide Exchange Factors (START) CUI: C0120465 / Source: MSH

Descendant Paths (Children/Leaves)

Descendant Path 1 (Top Source: MSH)

  1. Guanine Nucleotide Exchange Factors (START) CUI: C0120465 / Source: MSH
  2. Guanine Nucleotide-Releasing Factor 2 CUI: C0606868 / Source: MSH

Descendant Path 2 (Top Source: MSH)

  1. Guanine Nucleotide Exchange Factors (START) CUI: C0120465 / Source: MSH
  2. ras Guanine Nucleotide Exchange Factors CUI: C0210149 / Source: MSH
  3. ras-GRF1 CUI: C0379310 / Source: MSH

Descendant Path 3 (Top Source: MSH)

  1. Guanine Nucleotide Exchange Factors (START) CUI: C0120465 / Source: MSH
  2. ras Guanine Nucleotide Exchange Factors CUI: C0210149 / Source: MSH
  3. Son of Sevenless Proteins CUI: C0143087 / Source: MSH
  4. Son of Sevenless Protein, Drosophila CUI: C0246703 / Source: MSH

Descendant Path 4 (Top Source: MSH)

  1. Guanine Nucleotide Exchange Factors (START) CUI: C0120465 / Source: MSH
  2. ras Guanine Nucleotide Exchange Factors CUI: C0210149 / Source: MSH
  3. Son of Sevenless Proteins CUI: C0143087 / Source: MSH
  4. SOS1 Protein CUI: C0217396 / Source: MSH

Descendant Path 5 (Top Source: MSH)

  1. Guanine Nucleotide Exchange Factors (START) CUI: C0120465 / Source: MSH
  2. ral Guanine Nucleotide Exchange Factor CUI: C0378212 / Source: MSH

Descendant Path 6 (Top Source: MSH)

  1. Guanine Nucleotide Exchange Factors (START) CUI: C0120465 / Source: MSH
  2. Rho Guanine Nucleotide Exchange Factors CUI: C3658359 / Source: MSH
  3. Proto-Oncogene Proteins c-bcr CUI: C0072449 / Source: MSH
  4. Fusion Proteins, bcr-abl CUI: C0004891 / Source: MSH

Descendant Path 7 (Top Source: MSH)

  1. Guanine Nucleotide Exchange Factors (START) CUI: C0120465 / Source: MSH
  2. Rho Guanine Nucleotide Exchange Factors CUI: C3658359 / Source: MSH
  3. Proto-Oncogene Proteins c-vav CUI: C0139040 / Source: MSH

Descendant Path 8 (Top Source: MSH)

  1. Guanine Nucleotide Exchange Factors (START) CUI: C0120465 / Source: MSH
  2. Eukaryotic Initiation Factor-2B CUI: C0606869 / Source: MSH

Descendant Path 9 (Top Source: MSH)

  1. Guanine Nucleotide Exchange Factors (START) CUI: C0120465 / Source: MSH
  2. C9orf72 Protein CUI: C4505142 / Source: MSH

Descendant Path 10 (Top Source: MSH)

  1. Guanine Nucleotide Exchange Factors (START) CUI: C0120465 / Source: MSH
  2. T-Lymphoma Invasion and Metastasis-inducing Protein 1 CUI: C0919491 / Source: MSH

Unique Ancestor Paths Found: 2 | Unique Descendant Paths Found: 10 | Max Depth: 10 levels.