Classification Nuance. The OpenFDA dataset, which draws from the Structured Product Labeling (SPL) files, often includes multiple classification fields, and the specific string "Phosphate Binder [EPC]" may only be assigned to a single product. The other drugs are likely classified using: More Specific Classes: Many of those drugs (like sevelamer, ferric citrate, etc.) may be classified by their specific mechanism or chemical group, which also acts as a phosphate binder. Example: A drug might be classified as "Iron-Containing Compound [EPC]" or "Aluminum-Containing Compound [EPC]" instead of the more general "Phosphate Binder [EPC]". Different Classification Fields: The NDC data contains several classification fields. You might be checking the Established Pharmacological Class (pharm_class_epc), but the other drugs might be listed under: Mechanism of Action (pharm_class_moa), Physiological Effect (pharm_class_pe)
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Antirheumatic Agent [EPC]

NDC Number Brand Name Generic Name Manufacturer Dosage Form DEA Sch. Marketing Start Date
0037-4401 Depen Penicillamine Viatris Specialty LLC TABLET 1978-11-30
0088-2160 Arava leflunomide sanofi-aventis U.S. LLC TABLET, FILM COATED 1998-09-10
0088-2161 Arava leflunomide sanofi-aventis U.S. LLC TABLET, FILM COATED 1998-09-10
0088-2162 Arava leflunomide sanofi-aventis U.S. LLC TABLET, FILM COATED 1998-09-10
0254-2000 penicillamine penicillamine Endo USA, Inc. TABLET, FILM COATED 2020-01-02
0591-4171 Penicillamine Penicillamine Actavis Pharma, Inc. CAPSULE 2019-06-25
10702-277 Leflunomide Leflunomide KVK-Tech, Inc. TABLET 2020-07-23
10702-278 Leflunomide Leflunomide KVK-Tech, Inc. TABLET 2020-07-23
23155-043 leflunomide leflunomide Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. TABLET 2009-10-29
23155-044 leflunomide leflunomide Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. TABLET 2009-10-29
25010-705 Cuprimine penicillamine Bausch Health US, LLC CAPSULE 1970-12-04
35573-447 Leflunomide leflunomide Burel Pharmaceuticals, LLC TABLET, FILM COATED 2022-01-03
35573-448 Leflunomide leflunomide Burel Pharmaceuticals, LLC TABLET, FILM COATED 2022-01-03
42291-420 LEFLUNOMIDE LEFLUNOMIDE AvKARE TABLET 2019-06-13
42291-421 LEFLUNOMIDE LEFLUNOMIDE AvKARE TABLET 2019-06-13
43598-634 Penicillamine Penicillamine Dr. Reddy's Laboratories Inc. CAPSULE, GELATIN COATED 2020-08-04
46708-436 Leflunomide Leflunomide Alembic Pharmaceuticals Limited TABLET 2016-12-01
46708-437 Leflunomide Leflunomide Alembic Pharmaceuticals Limited TABLET 2016-12-01
49884-146 Penicillamine penicillamine Endo USA, Inc. CAPSULE 2020-01-08
50090-5992 Leflunomide Leflunomide A-S Medication Solutions TABLET, FILM COATED 2021-03-29
50090-7537 leflunomide leflunomide A-S Medication Solutions TABLET, FILM COATED 2019-04-26
50268-477 LEFLUNOMIDE LEFLUNOMIDE AvPAK TABLET 2020-09-17
50268-478 LEFLUNOMIDE LEFLUNOMIDE AvPAK TABLET 2020-09-17
51991-974 Penicillamine Penicillamine Breckenridge Pharmaceutical, Inc. CAPSULE 2021-11-12
59651-348 Leflunomide Leflunomide Aurobindo Pharma Limited TABLET, FILM COATED 2021-03-29
59651-349 Leflunomide Leflunomide Aurobindo Pharma Limited TABLET, FILM COATED 2021-03-29
60505-2502 LEFLUNOMIDE LEFLUNOMIDE Apotex Corp. TABLET 2005-09-13
60505-2503 LEFLUNOMIDE LEFLUNOMIDE Apotex Corp. TABLET 2005-09-13
62135-793 Leflunomide Leflunomide Chartwell RX, LLC TABLET 2009-10-29
62135-794 Leflunomide Leflunomide Chartwell RX, LLC TABLET 2009-10-29
62332-061 Leflunomide Leflunomide Alembic Pharmaceuticals Inc. TABLET 2016-12-01
62332-062 Leflunomide Leflunomide Alembic Pharmaceuticals Inc. TABLET 2016-12-01
63629-9728 Leflunomide Leflunomide Bryant Ranch Prepack TABLET, FILM COATED 2021-03-29
68071-3763 Leflunomide Leflunomide NuCare Pharmaceuticals, Inc. TABLET, FILM COATED 2020-08-31
68071-3764 leflunomide leflunomide NuCare Pharmaceuticals, Inc. TABLET, FILM COATED 2019-04-26
68475-201 Penicillamine Penicillamine Navinta LLC CAPSULE 2022-01-01
70010-907 Penicillamine Penicillamine Granules Pharmaceuticals Inc. CAPSULE 2020-12-21
70709-102 AAGYLUR Penicillamine Cycle Pharmaceuticals Ltd. CAPSULE 2025-09-25
70710-1157 leflunomide leflunomide Zydus Pharmaceuticals (USA) Inc. TABLET, FILM COATED 2019-04-26
70710-1158 leflunomide leflunomide Zydus Pharmaceuticals (USA) Inc. TABLET, FILM COATED 2019-04-26
70748-129 Leflunomide Leflunomide Lupin Pharmaceuticals, Inc. TABLET, FILM COATED 2020-08-31
70748-130 Leflunomide Leflunomide Lupin Pharmaceuticals, Inc. TABLET, FILM COATED 2020-08-31
70748-153 Penicillamine Penicillamine Lupin Pharmaceuticals, Inc. TABLET 2021-03-01
70771-1491 leflunomide leflunomide Zydus Lifesciences Limited TABLET, FILM COATED 2019-04-26
70771-1492 leflunomide leflunomide Zydus Lifesciences Limited TABLET, FILM COATED 2019-04-26
71205-916 Penicillamine Penicillamine Proficient Rx LP CAPSULE 2020-12-21
71335-2256 Leflunomide Leflunomide Bryant Ranch Prepack TABLET, FILM COATED 2021-03-29
71335-2403 leflunomide leflunomide Bryant Ranch Prepack TABLET, FILM COATED 2019-04-26
72162-2409 leflunomide leflunomide Bryant Ranch Prepack TABLET 2009-10-29
72162-2410 leflunomide leflunomide Bryant Ranch Prepack TABLET 2009-10-29



 [EPC] Established Pharmacological Classification 

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