Classification Nuance. The OpenFDA dataset, which draws from the Structured Product Labeling (SPL) files, often includes multiple classification fields, and the specific string "Phosphate Binder [EPC]" may only be assigned to a single product. The other drugs are likely classified using: More Specific Classes: Many of those drugs (like sevelamer, ferric citrate, etc.) may be classified by their specific mechanism or chemical group, which also acts as a phosphate binder. Example: A drug might be classified as "Iron-Containing Compound [EPC]" or "Aluminum-Containing Compound [EPC]" instead of the more general "Phosphate Binder [EPC]". Different Classification Fields: The NDC data contains several classification fields. You might be checking the Established Pharmacological Class (pharm_class_epc), but the other drugs might be listed under: Mechanism of Action (pharm_class_moa), Physiological Effect (pharm_class_pe)
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Chloride Channel Activator [EPC]

NDC Number Brand Name Generic Name Manufacturer Dosage Form DEA Sch. Marketing Start Date
0254-3028 Lubiprostone Lubiprostone Par Health USA, LLC CAPSULE, GELATIN COATED 2021-01-01
0254-3029 Lubiprostone Lubiprostone Par Health USA, LLC CAPSULE, GELATIN COATED 2021-01-01
0406-6408 Lubiprostone Lubiprostone SpecGx LLC CAPSULE, GELATIN COATED 2024-05-01
0406-6424 Lubiprostone Lubiprostone SpecGx LLC CAPSULE, GELATIN COATED 2024-05-01
0480-3479 Lubiprostone Lubiprostone Teva Pharmaceuticals, Inc. CAPSULE, GELATIN COATED 2023-01-03
0480-4138 Lubiprostone Lubiprostone Teva Pharmaceuticals, Inc. CAPSULE, GELATIN COATED 2023-01-03
23635-508 Amitiza lubiprostone SpecGx LLC CAPSULE, GELATIN COATED 2024-04-01
23635-524 Amitiza lubiprostone SpecGx LLC CAPSULE, GELATIN COATED 2024-04-01
31722-403 Lubiprostone lubiprostone Camber Pharmaceuticals, Inc. CAPSULE 2025-05-27
31722-404 Lubiprostone lubiprostone Camber Pharmaceuticals, Inc. CAPSULE 2025-05-27
42291-475 Lubiprostone Lubiprostone AvKARE CAPSULE 2023-01-04
42291-476 Lubiprostone Lubiprostone AvKARE CAPSULE 2023-01-04
43598-163 Lubiprostone Lubiprostone Dr. Reddy's Laboratories Inc. CAPSULE, GELATIN COATED 2023-01-01
43598-168 Lubiprostone Lubiprostone Dr. Reddy's Laboratories Inc. CAPSULE, GELATIN COATED 2023-01-01
51407-744 Lubiprostone lubiprostone Golden State Medical Supply, Inc. CAPSULE, GELATIN COATED 2008-04-29
51407-745 Lubiprostone lubiprostone Golden State Medical Supply, Inc. CAPSULE, GELATIN COATED 2006-01-31
55700-963 Lubiprostone Lubiprostone Quality Care Products, LLC CAPSULE, GELATIN COATED 2022-02-17
63304-351 Lubiprostone lubiprostone Sun Pharmaceutical Industries, Inc. CAPSULE, GELATIN COATED 2023-01-01
63304-352 Lubiprostone lubiprostone Sun Pharmaceutical Industries, Inc. CAPSULE, GELATIN COATED 2023-01-01
64764-080 Amitiza lubiprostone Takeda Pharmaceuticals America, Inc. CAPSULE, GELATIN COATED 2006-01-31
64764-240 Amitiza lubiprostone Takeda Pharmaceuticals America, Inc. CAPSULE, GELATIN COATED 2006-01-31
65162-841 Lubiprostone Lubiprostone Amneal Pharmaceuticals LLC CAPSULE 2021-12-03
65162-842 Lubiprostone Lubiprostone Amneal Pharmaceuticals LLC CAPSULE 2021-12-03
69339-162 LUBIPROSTONE LUBIPROSTONE Natco Pharma USA LLC CAPSULE 2022-10-17
69339-163 LUBIPROSTONE LUBIPROSTONE Natco Pharma USA LLC CAPSULE 2022-10-17
70710-1641 Lubiprostone Lubiprostone Zydus Pharmaceuticals USA Inc. CAPSULE 2023-03-23
70710-1642 Lubiprostone Lubiprostone Zydus Pharmaceuticals USA Inc. CAPSULE 2023-03-23
70771-1763 Lubiprostone Lubiprostone Zydus Lifesciences Limited CAPSULE 2023-03-23
70771-1764 Lubiprostone Lubiprostone Zydus Lifesciences Limited CAPSULE 2023-03-23
71205-831 Lubiprostone lubiprostone Proficient Rx LP CAPSULE, GELATIN COATED 2023-01-01
71205-832 Lubiprostone lubiprostone Proficient Rx LP CAPSULE, GELATIN COATED 2023-01-01
71205-834 Lubiprostone Lubiprostone Proficient Rx LP CAPSULE, GELATIN COATED 2023-01-01
72189-410 Amitza Lubiprostone Direct_Rx CAPSULE, GELATIN COATED 2023-01-12
72189-607 Lubiprostone Lubiprostone Direct Rx CAPSULE, GELATIN COATED 2025-01-16
72603-288 Lubiprostone lubiprostone Northstar Rx LLC CAPSULE 2025-07-01
72603-289 Lubiprostone lubiprostone Northstar Rx LLC CAPSULE 2025-07-01
76420-777 Lubiprostone Lubiprostone Asclemed USA, Inc. CAPSULE 2023-03-23
76420-778 Lubiprostone Lubiprostone Asclemed USA, Inc. CAPSULE 2023-03-23
76420-906 Lubiprostone lubiprostone Asclemed USA, Inc. CAPSULE, GELATIN COATED 2023-01-01
76420-907 Lubiprostone lubiprostone Asclemed USA, Inc. CAPSULE, GELATIN COATED 2023-01-01
80425-0354 Lubiprostone lubiprostone Advanced Rx of Tennessee, LLC CAPSULE, GELATIN COATED 2023-08-16
80425-0355 Lubiprostone lubiprostone Advanced Rx of Tennessee, LLC CAPSULE, GELATIN COATED 2023-08-16
82804-001 Lubiprostone Lubiprostone Proficient Rx LP CAPSULE, GELATIN COATED 2023-01-01
83008-001 Lubiprostone lubiprostone Quality Care Products, LLC CAPSULE, GELATIN COATED 2023-03-14



 [EPC] Established Pharmacological Classification 

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