Classification Nuance. The OpenFDA dataset, which draws from the Structured Product Labeling (SPL) files, often includes multiple classification fields, and the specific string "Phosphate Binder [EPC]" may only be assigned to a single product. The other drugs are likely classified using: More Specific Classes: Many of those drugs (like sevelamer, ferric citrate, etc.) may be classified by their specific mechanism or chemical group, which also acts as a phosphate binder. Example: A drug might be classified as "Iron-Containing Compound [EPC]" or "Aluminum-Containing Compound [EPC]" instead of the more general "Phosphate Binder [EPC]". Different Classification Fields: The NDC data contains several classification fields. You might be checking the Established Pharmacological Class (pharm_class_epc), but the other drugs might be listed under: Mechanism of Action (pharm_class_moa), Physiological Effect (pharm_class_pe)
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Complement Inhibitor [EPC]

NDC Number Brand Name Generic Name Manufacturer Dosage Form DEA Sch. Marketing Start Date
25682-001 SOLIRIS ECULIZUMAB Alexion Pharmaceuticals Inc. INJECTION, SOLUTION, CONCENTRATE 2007-04-02
25682-022 Ultomiris ravulizumab Alexion Pharmaceuticals Inc. SOLUTION, CONCENTRATE 2018-12-21
25682-025 Ultomiris ravulizumab Alexion Pharmaceuticals Inc. SOLUTION, CONCENTRATE 2020-10-09
25682-028 Ultomiris ravulizumab Alexion Pharmaceuticals Inc. SOLUTION, CONCENTRATE 2020-10-09
50474-990 ZILBRYSQ zilucoplan UCB, Inc. INJECTION, SOLUTION 2024-01-03
50474-991 ZILBRYSQ zilucoplan UCB, Inc. INJECTION, SOLUTION 2024-01-03
50474-992 ZILBRYSQ zilucoplan UCB, Inc. INJECTION, SOLUTION 2024-01-03
51759-208 EPYSQLI Eculizumab-aagh Teva Pharmaceuticals USA, Inc. INJECTION, SOLUTION 2025-04-07
55513-180 BKEMV eculizumab-aeeb Amgen Inc INJECTION, SOLUTION, CONCENTRATE 2025-03-01
61755-014 VEOPOZ Pozelimab Regeneron Pharmaceuticals, Inc. INJECTION, SOLUTION 2023-08-18
73606-010 Empaveli Pegcetacoplan Apellis Pharmaceuticals, Inc. INJECTION, SOLUTION 2021-05-14
73606-020 Syfovre Pegcetacoplan Apellis Pharmaceuticals, Inc. INJECTION, SOLUTION 2023-02-17



 [EPC] Established Pharmacological Classification 

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