Classification Nuance. The OpenFDA dataset, which draws from the Structured Product Labeling (SPL) files, often includes multiple classification fields, and the specific string "Phosphate Binder [EPC]" may only be assigned to a single product. The other drugs are likely classified using: More Specific Classes: Many of those drugs (like sevelamer, ferric citrate, etc.) may be classified by their specific mechanism or chemical group, which also acts as a phosphate binder. Example: A drug might be classified as "Iron-Containing Compound [EPC]" or "Aluminum-Containing Compound [EPC]" instead of the more general "Phosphate Binder [EPC]". Different Classification Fields: The NDC data contains several classification fields. You might be checking the Established Pharmacological Class (pharm_class_epc), but the other drugs might be listed under: Mechanism of Action (pharm_class_moa), Physiological Effect (pharm_class_pe)
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Dihydrofolate Reductase Inhibitor Antimalarial [EPC]

NDC Number Brand Name Generic Name Manufacturer Dosage Form DEA Sch. Marketing Start Date
0480-3720 Pyrimethamine Pyrimethamine Teva Pharmaceuticals, Inc. TABLET 2021-12-15
43598-672 Pyrimethamine pyrimethamine DR.REDDYS LABORATORIES INC TABLET 2020-03-16
59651-590 Pyrimethamine Pyrimethamine Aurobindo Pharma Limited TABLET 2022-10-25
69413-330 Daraprim pyrimethamine Vyera Pharmaceuticals LLC TABLET 1953-01-23
72603-262 Pyrimethamine Pyrimethamine NorthStar Rx LLC TABLET 2024-10-01
72647-330 Pyrimethamine pyrimethamine OAKRUM PHARMA, LLC TABLET 2020-03-13
83649-330 Daraprim pyrimethamine TILDE Sciences LLC TABLET 1953-01-23



 [EPC] Established Pharmacological Classification 

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