Classification Nuance. The OpenFDA dataset, which draws from the Structured Product Labeling (SPL) files, often includes multiple classification fields, and the specific string "Phosphate Binder [EPC]" may only be assigned to a single product. The other drugs are likely classified using: More Specific Classes: Many of those drugs (like sevelamer, ferric citrate, etc.) may be classified by their specific mechanism or chemical group, which also acts as a phosphate binder. Example: A drug might be classified as "Iron-Containing Compound [EPC]" or "Aluminum-Containing Compound [EPC]" instead of the more general "Phosphate Binder [EPC]". Different Classification Fields: The NDC data contains several classification fields. You might be checking the Established Pharmacological Class (pharm_class_epc), but the other drugs might be listed under: Mechanism of Action (pharm_class_moa), Physiological Effect (pharm_class_pe)
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Direct Thrombin Inhibitor [EPC]

NDC Number Brand Name Generic Name Manufacturer Dosage Form DEA Sch. Marketing Start Date
0143-9288 Argatroban Argatroban Hikma Pharmaceuticals USA Inc. INJECTION 2012-01-05
0143-9377 Argatroban Argatroban Hikma Pharmaceuticals USA Inc. INJECTION 2020-03-25
0143-9559 Argatroban Argatroban Hikma Pharmaceuticals USA Inc. INJECTION 2016-11-01
0143-9674 Argatroban Argatroban Hikma Pharmaceuticals USA Inc. INJECTION 2012-01-05
0409-1140 Argatroban Argatroban Hospira, Inc. INJECTION, SOLUTION 2017-03-06
16729-275 Bivalirudin bivalirudin Accord Healthcare, Inc. INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 2018-11-07
16729-430 ARGATROBAN Argatroban Accord Healthcare Inc. INJECTION 2021-10-07
25021-414 Argatroban Argatroban Sagent Pharmaceuticals INJECTION, SOLUTION 2021-04-15
42023-182 Argatroban Argatroban Endo USA, Inc. INJECTION 2015-06-01
42023-622 Bivalirudin Bivalirudin Endo USA, Inc. INJECTION, SOLUTION 2023-06-19
48951-5112 Hamamelis Aesculus Hamamelis Aesculus Uriel Pharmacy Inc PELLET 2009-09-01
52958-034 Bivalirudin Bivalirudin Hainan Shuangcheng Pharmaceuticals Co., Ltd. INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 2019-10-23
55111-652 Bivalirudin Bivalirudin Dr. Reddy's Laboratories Limited INJECTION 2017-05-31
55150-210 BIVALIRUDIN BIVALIRUDIN Eugia US LLC INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 2018-07-27
55150-241 Argatroban Argatroban Eugia US LLC INJECTION, SOLUTION 2018-11-27
63323-526 Argatroban Argatroban Fresenius Kabi USA, LLC INJECTION, SOLUTION 2015-03-23
63323-562 Bivalirudin Bivalirudin Fresenius Kabi USA, LLC INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 2016-10-28
65145-126 ARGATROBAN Argatroban Caplin Steriles Limited INJECTION 2024-10-04
65219-429 Argatroban Argatroban Fresenius Kabi USA, LLC INJECTION 2021-05-24
67457-212 Argatroban argatroban Mylan Institutional LLC INJECTION, SOLUTION 2017-11-14
67457-256 Bivalirudin bivalirudin Mylan Institutional LLC INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 2018-06-05
68083-141 Argatroban Argatroban Gland Pharma Limited SOLUTION 2017-05-26
68083-568 Argatroban Argatroban Gland Pharma Limited INJECTION, SOLUTION 2023-07-31
70121-1037 Argatroban Argatroban Amneal Pharmaceuticals LLC INJECTION, SOLUTION 2018-01-26
70436-025 bivalirudin bivalirudin Slate Run Pharmaceuticals, LLC INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION 2021-06-30
70511-142 Bivalirudin Bivalirudin MAIA Pharmaceuticals, Inc. INJECTION, SOLUTION 2024-05-27
71288-427 BIVALIRUDIN BIVALIRUDIN Meitheal Pharmaceuticals Inc. INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 2018-07-16
72572-035 bivalirudin bivalirudin Civica, Inc. INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 2020-12-21
75929-217 bivalirudin bivalirudin Pharma Packaging Solutions, LLC dba Tjoapack LLC INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 2020-12-21
83634-400 Bivalirudin bivalirudin Avenacy, Inc. INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 2023-12-18



 [EPC] Established Pharmacological Classification 

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