Classification Nuance. The OpenFDA dataset, which draws from the Structured Product Labeling (SPL) files, often includes multiple classification fields, and the specific string "Phosphate Binder [EPC]" may only be assigned to a single product. The other drugs are likely classified using: More Specific Classes: Many of those drugs (like sevelamer, ferric citrate, etc.) may be classified by their specific mechanism or chemical group, which also acts as a phosphate binder. Example: A drug might be classified as "Iron-Containing Compound [EPC]" or "Aluminum-Containing Compound [EPC]" instead of the more general "Phosphate Binder [EPC]". Different Classification Fields: The NDC data contains several classification fields. You might be checking the Established Pharmacological Class (pharm_class_epc), but the other drugs might be listed under: Mechanism of Action (pharm_class_moa), Physiological Effect (pharm_class_pe)
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Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme [EPC]

NDC Number Brand Name Generic Name Manufacturer Dosage Form DEA Sch. Marketing Start Date
54092-700 ELAPRASE idursulfase Takeda Pharmaceuticals America, Inc. SOLUTION, CONCENTRATE 2006-07-24
58468-0070 ALDURAZYME laronidase Genzyme Corporation INJECTION, SOLUTION, CONCENTRATE 2003-04-30
68135-020 NAGLAZYME galsulfase BioMarin Pharmaceutical Inc. SOLUTION 2005-06-09
68135-100 VIMIZIM elosulfase alfa BioMarin Pharmaceutical Inc. INJECTION, SOLUTION, CONCENTRATE 2014-02-14



 [EPC] Established Pharmacological Classification 

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