Classification Nuance. The OpenFDA dataset, which draws from the Structured Product Labeling (SPL) files, often includes multiple classification fields, and the specific string "Phosphate Binder [EPC]" may only be assigned to a single product. The other drugs are likely classified using: More Specific Classes: Many of those drugs (like sevelamer, ferric citrate, etc.) may be classified by their specific mechanism or chemical group, which also acts as a phosphate binder. Example: A drug might be classified as "Iron-Containing Compound [EPC]" or "Aluminum-Containing Compound [EPC]" instead of the more general "Phosphate Binder [EPC]". Different Classification Fields: The NDC data contains several classification fields. You might be checking the Established Pharmacological Class (pharm_class_epc), but the other drugs might be listed under: Mechanism of Action (pharm_class_moa), Physiological Effect (pharm_class_pe)
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Reducing and Complexing Thiol [EPC]

NDC Number Brand Name Generic Name Manufacturer Dosage Form DEA Sch. Marketing Start Date
0093-7909 Tiopronin Tiopronin Teva Pharmaceuticals USA, Inc. TABLET, SUGAR COATED 2021-05-17
0178-0900 Thiola tiopronin Mission Pharmacal Company TABLET, SUGAR COATED 1988-08-11
0178-0901 Thiola EC tiopronin Mission Pharmacal Company TABLET, DELAYED RELEASE 2019-06-28
0178-0902 Thiola EC tiopronin Mission Pharmacal Company TABLET, DELAYED RELEASE 2019-06-28
0254-3034 TIOPRONIN TIOPRONIN Endo USA, Inc. TABLET, DELAYED RELEASE 2024-06-26
0254-3035 TIOPRONIN TIOPRONIN Endo USA, Inc. TABLET, DELAYED RELEASE 2024-06-26
0480-7824 Tiopronin Tiopronin Teva Pharmaceuticals, Inc. TABLET, DELAYED RELEASE 2024-10-08
0480-9227 Tiopronin Tiopronin Teva Pharmaceuticals, Inc. TABLET, DELAYED RELEASE 2024-10-08
13668-691 TIOPRONIN tiopronin Torrent Pharmaceuticals Limited TABLET, DELAYED RELEASE 2024-01-30
13668-692 TIOPRONIN tiopronin Torrent Pharmaceuticals Limited TABLET, DELAYED RELEASE 2024-01-30
44523-054 Tiopronin Tiopronin BioComp Pharma, Inc. TABLET, DELAYED RELEASE 2024-12-05
44523-055 Tiopronin Tiopronin BioComp Pharma, Inc. TABLET, DELAYED RELEASE 2024-12-05
60219-2009 tiopronin tiopronin Amneal Pharmaceuticals NY LLC TABLET, DELAYED RELEASE 2023-08-16
70709-121 VENXXIVA tiopronin Cycle Pharmaceuticals Ltd. TABLET, DELAYED RELEASE 2025-01-22
70709-123 VENXXIVA tiopronin Cycle Pharmaceuticals Ltd. TABLET, DELAYED RELEASE 2025-01-22



 [EPC] Established Pharmacological Classification 

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